A Practice Note discussing the leniency program of the Antitrust Division of the US Department of Justice (DOJ) for antitrust violations. It focuses on the corporate and individual leniency programs, including a discussion of the requirements for leniency, the timing of leniency applications, eligible individuals, the cooperation requirement, leniency plus, penalty plus, and the potential for reduction of antitrust civil penalties under the Antitrust Criminal Penalty Enhancements and Reform Act of 2004 (ACPERA).